MINIATURIZED SHAKE-FLASK HPLC METHOD FOR DETERMINATION OF DISTRIBUTION COEFFICIENT OF DRUGS USED IN INFLAMMATORY BOWEL DISEASES

Miniaturized shake-flask HPLC method for determination of distribution coefficient of drugs used in inflammatory bowel diseases

A new method for determination of distribution coefficient of drugs azathioprine, 6-mercaptopurine and 6-thioguanine and nutrient folic acid used buffalo bills big chain necklace in the treatment of inflammatory bowel disease based on a miniaturized shake-flask and HPLC/DAD was developed.Special attention was made to the most commonly reported prob

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The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

Low density lipoprotein (LDL) cholesterol is taken up into cells via clathrin-mediated endocytosis of the LDL receptor (LDLR).Following dissociation of the LDLR-LDL complex, LDL is directed to lysosomes whereas classic carlectables - recent releases the LDLR recycles to the plasma membrane.Activation of the sterol-sensing nuclear receptors liver X

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Comparison and evaluation of neutralization of clinically frequently used antimicrobial agents using three different culture media in simulated blood cultures

ABSTRACT The performance of BACT/ALERT FA/FN Plus (France) blood culture containing a novel resin, DL (China) blood culture containing common resin, and adsorbent-free REDOX (USA) blood culture relying on dilution for antimicrobial fairytale once upon a time theme party neutralization at %peak serum concentration was evaluated by measuring the reco

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Hydro-thermal conditions and their impact on irradiance and hygro-thermal use efficiency of wheat in central Punjab

The experiments were conducted to develop indices to provide critical insights into crop phenology and yield responses of wheat to thermal and moisture conditions during rabi 2021-22 and 2022-23 at PAU, Ludhiana, Punjab.The wheat variety Unnat PBW was sown on three dates (D1: 27th October, D2: 17th November, D3: 8th December) under three irrigation

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